Elementary Bodies in Bovine Malignant Catarrh

An Observation on Bovine Malignant Catarrh in Japan

Constituents of Elementary Bodies of Vaccinia

Suspensions of purified elementary bodies of vaccinia exhibit fluorescence in the presence of ultraviolet light. This fluorescent constituent can be separated by chromatographic methods provided the virus is first denatured by acid and heat. By means of the specific protein of d-amino acid oxidase it has been possible to identify the flavin constituent as flavin-adenine-dinucleotide and show th...

Some Constituents of Elementary Bodies of Vaccinia

Treatment of elementary bodies of vaccinia with dilute solutions of sodium hydroxide resulted in the extraction of certain soluble materials accounting for half of the dry weight of the virus. Elementary bodies contained about 0.4 per cent inorganic phosphorus, practically all of which occurred in the form of a nucleoprotein containing thymus nucleic acid. In addition, a substance was recovered...

Electrophoretic Studies on Elementary Bodies of Vaccinia

Electrophoretic studies were made on vaccine virus, collodion particles, and glass particles suspended in 0.01 molar buffer solutions at pH 7.9, in which the moving boundary method was used. In some experiments, uncoated particles were used; in others, particles were coated with proteins and then resuspended in the buffer solution after a washing; in still others, an excess of protein which had...

Infectious Catarrh of Mice

A natural outbreak of an infectious catarrh in a colony of Swiss mice is reported. The disease was generally characterized by a peculiar chattering sound during life and by a rhinitis, an otitis media, and a pneumonia at autopsy. The pneumonia was slowly progressive and terminated fatally in a high percentage of cases. The mortality in a group of 75 naturally infected mice was 95 per cent over ...